Sentence examples for this highly challenging from inspiring English sources

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Then the question is: Are we ready to assume this collective agency, or as the UNESCO General Assembly Resolution 37 C/57 Article 11(b) urges us, "to act as change agents" in this highly challenging aspect of sustainable development?

This will assist fruit biologists, postharvest scientists and pear breeders to develop an understanding of the genetic control of this highly challenging postharvest disorder.

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However, from a computational point of view this is highly challenging since the set of transformations by which the random walks are generated (for details see Materials and Methods) have to guarantee that mother and daughter strands stay connected at the replication fork by preserving the self-avoidance of the chain.

Yet, due to the limited amount of NKT cells in cord blood this approach is highly challenging.

Therefore, using primary human B cells in this assay is highly challenging given the relatively low numbers of isolated B cells from peripheral blood.

This integration remains highly challenging because model systems offering a rich ecological and evolutionary background, together with the availability of developmental genetic tools and genomic resources, are scarce.

In theory, study data can be anonymised and made suitable for data sharing; however, this has proved highly challenging in practice and risks of disclosure remain in many datasets.

A preoperative diagnosis of IgG4-related cholecystitis, although possible, would have been highly challenging in this case.

This makes the problem of optimal distributed load management highly challenging.

However, with repeated sequences, transposons, retrotransposons, and sequence gaps in this region, cloning of a large DNA fragment is still highly challenging.

Despite this progress in neurosciences, the development of CNS-active drugs remains highly challenging as shown by relatively high attrition rates of drugs during clinical trials (2).

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