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This granddaughter design included 1 548 artificial insemination bulls distributed in 14 sire families and evaluated after a progeny-test for 24 traits (production, milk composition, persistency, type, fertility, mastitis resistance, and milking ease).
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Furthermore, if the difficulties in status prediction are indeed due to the presence of multiple QTL in the same interval, then this will cause the same problems in status prediction using the granddaughter design.
Quantitative trait loci affecting economically important traits were studied for eight large US Holstein grandsire families by using the granddaughter design.
An approach somewhat similar to the granddaughter design for detecting quantitative trait loci in dairy cattle was followed.
Quantitative trait loci affecting milk yield, health, and conformation traits were studied for eight large US Holstein grandsire families by using the granddaughter design.
Quantitative trait loci (QTL) affecting the shape and scale of lactation curves for production and health traits in dairy cattle were mapped in three U.S. Holstein families (Dairy Bull DNA Repository families one, four, and five) using the granddaughter design.
Preliminary marker association results for quantitative trait loci affecting conformation traits using the granddaughter design and 8 large US Holstein grandsire families revealed strong associations in two families between the predicted transmitting abilities for dairy conformation and marker genotypes on bovine chromosome 27.
An association analysis was conducted in the German Holstein-Friesian population to test the association between the single nucleotide polymorphism (SNP) at position +777 within the CXCR1 gene and the SNP at position −1768 in the 5′ upstream region of this gene (rs41255711) and the indicator trait SCS by using a granddaughter design.
Ten grandsire families were used in a granddaughter design.
The mapping population consisted of 12 bulls and their 491 sons in a granddaughter design.
A statistical model was applied to a granddaughter design to analyze 16 German Holstein families.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com