Sentence examples for this formidable problem from inspiring English sources

It was essential to provide the tools to magistrates and judges, who were confronted by the accused sorcerers, in order to face this formidable problem.

However, the formidable problem in efficient mapping of applications (mostly loop algorithms) onto such architectures has been a hindrance in their mass acceptance.

Two recent reviews have dealt with the formidable problem of identification of drugs with improved efficiency and cancer selectivity (Benson et al, 2006; Collins and Workman, 2006).

Thus, our main incentive with the present analysis was to deconstruct the formidable problem of the emergence of translation into a series of plausible and manageable steps, in accordance with the Continuity Principle.

Here, however, we address the formidable problem of the origins of translation within the Continuity Principle, by harnessing evidence from comparative analysis of the translation system components, theoretical and experimental work on the hypothetical primordial RNA world, and the experimental study of interactions between amino acids and their codons and anticodons.

Wimsatt uses these disanalogies to highlight the formidable problems facing any effort to use population genetic models in the explanation of cultural change.

This may already pose a formidable problem as some bacteria might only express narrow pores or mutations might lead to decreased expression of porins, porin loss, or narrow channels [ 4].

This study provides evidence that GBV remains a formidable problem in Thai Nguyen province with serious reproductive health consequences for the women who live there.

That was a formidable problem.

But corruption remains a formidable problem.

Like Yau, Perelman was a formidable problem solver.