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Intra-articular delivery is under consideration, but because joints have very efficient lymphatic clearance systems the utility of this form of targeting remains to be proved.
Targets are represented in the data in the form of target descriptors and this is combined with compound descriptors.
Top-down attention, in the form of target predictability, was associated with an improvement in search performance that was comparable for younger and older adults.
These identified miRNA targets using degradome sequencing are present in the form of target plots (t-plots) that plot the abundance of the signatures relative to their position in the transcripts [ 30].
The identified miRNA targets using degradome sequencing are presented in the form of target plots (t-plots) that plot the abundance of the signatures relative to their position in the transcript [ 14].
I particularly appreciated the effort to link genotypes to phenotypes in the form of "target organ toxicity patterns"—in liver, kidney, lung, nervous system, skin, reproductive system -from Chapter 1 onward.
However, we find that, in the absence of adjuvant, Ab responses are weak and show that this form of antigen targeting does not inevitably lead to CD4+ T-cell priming but, rather, can be used to favor the conversion of antigen-specific naïve CD4+ T cells into Foxp3+ suppressive cells.
As a result many opt for what appears to be the safe option in the form of target-date funds (in America) or default funds (in Britain).
On Facebook, that can now take the form of targeting users who have already installed a mobile app and then presenting them with custom calls to action.
However, the rise of next generation sequencing in clinical care, in the form of targeted panel testing and whole genome sequencing 1 and the mainstreaming of genetic medicine have greatly increased the prevalence of such familial disclosure issues.
We suggest that one possible rationale behind this form of sanction is targeting group-specific deterrence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com