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If this finding is validated in subsequent genetic and molecular studies, it would suggest that TDP-43 plays a role in the modulation of synaptic homeostasis via the dpp /BMP signaling cascade.
This finding is validated through national surveys reporting low utilization of reproductive health services by Pakistani women like contraception, tetanus toxoid vaccination, antenatal care and delivery by skilled birth attendant [ 7, 24, 40].
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This finding was validated both in vitro and in vivo, with EZH2 overexpression proving sufficient to drive proliferation in cancer cells and transform primary fibroblasts (Bracken et al., 2003; Croonquist and Van Ness, 2005).
This finding was validated by the GSEA analysis of mRNA expression data (Figure 5B).
This finding was validated in the geographically, genetically and demographically distinct Ugandan pediatric population, where ANG-1 (AUC: 0.785, p<0.001) and the ANG-2∶ANG-1 rAUCo (AUC: 0.779, p<0.001) were still the best of the biomarkers examined (Figure 2B, Table 3; sICAM-1, data not shown).
Importantly, this finding was validated in an independent dataset [ 49].
This finding was validated by careful diagnostic review of morphology and comparison with IHC findings.
This finding was validated in a second, independent cohort of women treated for eBC.
This finding was validated by RT-PCR in liver (FC = 13.15, p = 0.0005).
This finding was validated by RT-qPCR in both SD-1 and Namalwa cells.
This finding was validated by IHC, which demonstrated enhanced protein expression in normal versus tumour tissue (p < 0.001).
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