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Together, these results indicate that Bmpr1a− / − ESCs are eliminated by apoptosis when in the presence of wild-type cells and that this elimination is not specific to any particular lineage.
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This elimination was not accompanied by a compensating rise in import tariffs for products formerly protected by such mechanisms; in other words, there was no tariffication of these past restrictions.
However, as a result of mutations to the urate oxidase gene during evolution, this pathway for urate elimination is not functional in humans.
These results suggest that reductive elimination is not rate-determining for this substrate combination, regardless of ligand bite angle.
In addition, renal elimination is not relevant since IgG antibodies are eliminated via catabolism and endocytosis; in the specific case of trastuzumab it has been reported that its elimination is not affected in patients with renal failure [ 34].
The unique IRIS safety-by-design approach is discussed, which, by eliminating accidents, at the design stage, or decreasing their consequences/probabilities when outright elimination is not possible, provides a very powerful first level of defense in depth.
Occasionally, as in this case, the slower rate of absorption as compared to the rate of elimination is not a straightforward conclusion to be drawn.
The process of climbing fiber elimination is not well understood, and the Inpp4a mutant appears unique in this defect.
Elimination is not a word that can be found in the owner's dictionary.
What the Zambia study confirms is that the challenge sleeping sickness poses to communities is a real and enduring one as elimination is not synonymous with eradication.
Such elimination is not going to happen as long as the current regime stays in power, and its collapse, while highly probable in the long run, is unlikely to occur in the near future.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com