Even two individual polymorphisms showed differential distribution of variant alleles between cases and controls, the effect nevertheless was marginal and a chance factor could no be ruled.
This gene dosage effect nevertheless strengthens the possibility that there is a real association between GSTM1 CNV and risk for RA in this subset of older non-smoking women.
While punctuated molecular evolution may be less frequent in animals (18% of cases versus 44% and 60% in plants and fungi, respectively [ 52]), this effect is nevertheless a prime candidate to explain the strong and persistent discrepancy between molecular- and fossil-based divergence estimates.
In the shooter for example, whenever a player character jumps across the screen, panels of neon light up in the background as he passes – it's really subtle, but a pleasing effect, nevertheless.
Nevertheless, this effect has not been fully identified yet.
All effects nevertheless appear to exist in the short-term only.
Blockade of TNF, using current biologics, has had profound therapeutic effects; nevertheless, between 30% and 40% of RA patients do not respond to this treatment.
Our results suggest that these dietary supplements could have beneficial effects; nevertheless continued studies are required before they could be recommended as a routine treatment in muscle diseases.
Nevertheless, this effect is not absolute, as seen with chaperone E. The reason is still unclear.
Nevertheless, this effect is negatively moderated by social support.
