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Finally, this dual action of L-Lactate on the activity of NR2B-containing NMDARs is also dependent on the extracellular L-Lactate concentration.
This dual action may be the result of their radical scavenging properties and their effects on cell-cycle checkpoints that are activated in response to radiation-induced chromosomal damage.
We study a particular example of this dual action in the context of quantum control and measurement of atomic spins through the light-shift interaction with an off-resonant optical probe.
Further research is needed to understand why and how certain sirtuins have both oncogenic or tumor-suppressive roles, and how this dual action may be best exploited for cancer management.
Indeed, this dual action of ERK is well represented in the nervous system: here the neurotrophin and activity dependent activation of ERK1/2 is very fast occurring within minutes from stimulus onset [47], [48].
This dual action leads to an improved time course of islet hormone secretion after a meal and in hyperglycemia.
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This point illustrates the dual action of oestrogen, both anti- and pro-inflammatory.
The NEDD8 E3 activity in this case is provided by the dual action of DCN1 [ 17- 19] and the RING subunit of the CRL complex [ 20- 22].
Based on results in Fig. 3a, this activity could be due to the dual action on both ECRF24 and A2780 cells.
This work aims to elucidate the mechanisms underlying the dual action of these polyphenols and investigates under which conditions they exhibit radioprotecting or radiosensitizing properties.
We construct on M2 an action of the other structure, which can be considered as the dual action.
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