Sentence examples for this domain allows from inspiring English sources

This domain allows XIAP to auto-ubiquitinate and self-degrade under severe apoptotic stress [20], [21] but can also promote the ubiquitination and degradation of caspases [22] and thus suppress apoptosis in conditions of lower apoptotic stress [23].

In the proteins MBD1, MBD2, MBD4, and MeCP2, this domain allows the specific recognition of DNA containing methylated cytosine; as a consequence, the proteins serve as interpreters of DNA methylation, an essential epigenetic mark.

Structural diversity in this domain allows MerR family proteins to sense not only various metal ions, e.g., Zn2+ by ZntR, Au+ by GolS, Cd2+ by CadR, Pb2+ by PbrR, or Hg2+ by MerR, but also oxidative stress, e.g., by SoxR via an [2Fe-2S]2+ cluster (reviewed in [131].

This domain allows ROQUIN to repress an enzyme called AMPK, which normally blocks cell growth by regulating cell metabolism.

This domain allows binding to GTPase Rab5 necessary for Rab5-dependent recruitment of Rabaptin5 to early endosomal membranes [ 27].

This domain allows negative regulation of the low-affinity transporters by the low-phosphate-induced Spl2 protein (Wykoff et al., 2007).

RINGs are characterized by a regular spacing of conserved cysteines and histidines which bind two Zn2+ ions that stabilize the overall structure of this domain, allowing for recognition and activation of E2 Ub-conjugating enzymes [ 2].

The evolution of an overlapping lipid- and Ca2+/CaM-binding site in mammalian STIM2 K-rich domain allows this sensor protein to integrate information of [Ca2+] in the cytosol as well as in the ER lumen.

This assembly mode of the kinase domain allows locating the epimerase domain further away from the hexamerization plane and is consistent with the proposition that the interdomain segment (residues 360 382) is the site of trimerization [18].

This finding is important because it indicates that the standardised CRQ dyspnoea domain allows for better discrimination between different degrees of COPD severity.

The processing in the temporal domain allows for a straightforward emulation of the forward temporal masking.