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We note that this does not introduce any additional overhead because we utilize an existing signaling procedure between macro UEs and eNBs.
At one level this does not introduce much bias: birds that are not present in a habitat cannot breed.
However, this does not introduce any bias in favour of any of the clustering algorithms.
For example, scenario (ii) may be preferred because this does not introduce an additional event in the parent.
Quite interestingly, WAP does not outperform WA: even if we construct a specific weighted network for each MeSH disease this does not introduce a significant advantage (at least, on the average).
Although the reference D. melanogaster genome is derived from a non-African lab strain, a previous simulation study using whole-genome sequences from African and European flies showed that this does not introduce a bias in the number of mapped reads per population (Catalán et al. 2012).
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Our opinion, however, is that this did not introduce any systematic bias.
In this study we found substantial non-participation but this did not introduce significant bias to cross-sectional population parameters.
However, the initial LBP intensity was not different between LBP episodes with maintained or decreased LTPA, and therefore this did not introduce such a bias into these comparisons.
We were not able to obtain kinase activity information from all patients, but this did not introduce bias, as all comparisons were between patients with known status.
We argue that this did not introduce a substantial bias since patients in most of our pre-specified conditions are usually hospitalized.
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