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The efferocytosis process of phagocytic uptake of apoptotic cells by macrophages is frequently disrupted in COPD tissue, and this disruption is thought to potentiate the chronic state of inflammation in the diseased lung.
The p53 pathway is frequently disrupted in Burkitt's lymphoma (BL) cells, and this disruption is now considered as an essential part of the tumorigenic process.
Importantly, the expression of many of these factors that are bivalently marked and regulated by PcG and TrxG is disrupted in various models of prenatal alcohol exposure; moreover, this disruption is associated with profound errors in neuronal patterning.
Staffing arrangements and shift working have also been shown to be disruptive and with the implementation of the European Working Time Directive, this disruption is likely to continue and to impact on the training of tomorrow's doctors".
The disruptive potential of this regime, but also Thomas's success resisting this disruption, is indicated in his response that "(i t hasn't stopped me doing anything I want to do".
Some of this disruption is good, and some bad.
But at some point, this disruption is on Wilson.
This disruption is hypothesized to reflect abnormalities in sensorimotor gating.
EasyJet said: "Despite the fact that this disruption is beyond easyJet's control, we will do everything possible to minimise the inconvenience to our customers.
"This disruption is expensive as well as inconvenient, with one estimate valuing the loss to the economy from roadworks congestion at £4bn a year.
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In addition, several NUMTs in H. magnipapillata were disrupted through transposable elements, while this disruption was not observed in N. vectensis.
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