Research has found that presenting for treatment and early management of the disease is compounded by issues related to geography (access to medical facility), income (cost of healthcare), or cultural differences (attitudes towards illness and disease) which prevent lower socio-economic groups from receiving treatment, increasing the risk of adverse outcomes.
The difficulty in making a correct diagnosis of Chagas disease is compounded in Japan by low awareness and recognition of the disease by medical staff; scarcity of epidemiologic or statistical data; and lack of diagnostic tools, resources, and facilities available to help with the differential diagnosis.
Most individuals with ABCA4-associated retinal disease are compound heterozygotes (3, 4), making it difficult to deduce the specific pathogenic contribution of individual alleles.
Early childhood caries is a highly destructive dental disease which is compounded by the need for young children to be treated under general anaesthesia.
This is compounded when several diseases have many overlapping features.
This problem of complexity is compounded by disease heterogeneity: patients with similar clinical manifestations may have different underlying disease mechanisms.
Given the re-emergence of tuberculosis in Europe and beyond, the search for novel bio-active compound classes against this disease is of utmost importance.
A20 NEW YORK/REGION B1-6 For Many Asians, America Means Pounds and Peril Asians, especially those from Far Eastern nations like China, Korea and Japan, are acutely susceptible to Type 2 diabetes, the most common form of the disease, a factor that is compounded by a sudden collision with and adaptation to the American diet.
Poverty places these patients at increased risk of chronic disease morbidity, that burden is compounded by the unknown and likely questionable practices of Bangladeshi IAPs.
This is particularly relevant for youth living with chronic diseases, especially if it is compounded by obesity [ 93], as there is a significant mental health burden associated being obese as a child or adolescent [ 94].
