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As a consequence, mother milk supplementation is often discontinued at the end of hospitalisation and hospital discharge, and this discontinuation exposes the infants to an increased risk of nutritional deficit.
In conclusion, 1/3 of patients with ACS discontinue > or =1 of their prescribed EBMs within 3 months of hospital discharge, and most of this discontinuation is without provider involvement.
The Africa Centre site systematically collected participant responses to this discontinuation.
We also suggest that genetic polymorphisms in the genes encoding the dopamine receptor (DR) are associated with this discontinuation.
To account for this discontinuation of patients during trials, statistical analyses often use the last observation carried forward (LOCF) approach to account for missing data.
These recommendations concerning the need to minimize lithium and valproate discontinuation, and any risks resulting from this discontinuation, may have relevance well beyond the VHA.
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In this context, the discontinuation rate was set at 8.9% and 8.0% for rivaroxaban and VKA, respectively as concerns the initial cycle and at 4.39% and 4.46%, respectively in subsequent cycles, based on data from the ROCKET AF trial.
This latter discontinuation rate is consistent with the 4.4% of patients who discontinued due to an ocular adverse event in the CLEAR study [ 14].
In this data discontinuation dates were set externally e.g. from an involved physician.
Bisphosphonates bind to bone hydroxyapatite for almost 10 years, and because of this reason, discontinuation of bisphosphonate administration before dental treatment is still disputable [26].
This assessed discontinuation risks in a mixed group of patients, but having only 20% of the cohort without diagnosed CVD and following up patients for only 1 year.
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