Sentence examples for this difficulty requires from inspiring English sources

How we deal with this difficulty requires sensitivity to competing interests, now and in the future, and a full appreciation of legal, social, technical, economic, and ethical considerations.

To overcome this difficulty requires the use of special simulation techniques (Li and Scheraga 1987; Rahman and Tully 2002; Minary et al. 2004; Curuksu and Zacharias 2009) to achieve effective sampling of conformational space.

Understanding this difficulty requires an appreciation of how Notch is activated: binding of DLL1 or Jag1 ligands to the Notch extra-cellular domain triggers a conformational change that exposes a β-strand of Notch to cleavage by ADAM family metalloproteases [41], [42].

McAvoy, who as also a former in-house counsel for Morgan Stanley, noted the difficulty required to bring in these kind of charges.

"Complexity" is a qualitative measure that involves the diagnostic difficulty, the difficulty of case management (i.e. the need for recuts or special stains) and the difficulty required in expressing a complete and meaningful diagnostic report.

The assessment of voiding difficulty requires the control of several confounders: hydration status, administration of agents during GA [ 9].

Overcoming these difficulties requires great efforts in interagency team building (biologists, animal health specialists, public health investigators, authorities) and involvement and education of the public [ 86].

This early onset deficit may relate to the degree of difficulty required to perform accurately in a task that maximizes both spatial information processing and flexible working memory representations.

This is achieved by estimating the learner's current knowledge in a discrete model of this problem space, and by using this representation to present the learner with problems at the level of difficulty required to maintain the desired success rate.

It escapes its period with difficulty, requiring the kind of treatment it received on Wednesday.

But it has long faced financial difficulty, requiring several cash infusions from outside investors.