All these difficulties notwithstanding, it seems that we have identified a parameter that may be associated with cetuximab clinical benefit.
53 These difficulties notwithstanding, it would be immensely valuable to identify bone change-related genes because many may fall in pathways that are more amenable to therapeutic modification than pathways specific for bone acquisition.
Giles' notion of quantitas materiae, which is not only generically extension or three-dimensionality, but seems to represent an unchangeable given "amount" of matter pertaining to a body, has been considered comparable, some difficulties notwithstanding, to the modern notion of mass (Donati 1988).
These difficulties notwithstanding, it is apparent that CAM use continues to be significant.
These difficulties notwithstanding, control selection needs to focus on endometriosis-free women who are representative of the population from which cases are drawn.
These limitations and difficulties notwithstanding, the value of paired genomic and epigenetic centromere datasets has been amply demonstrated in studies from human, plant, and Drosophila genomes that have been valuable for defining current models of centromere specification, identity and function [ 9, 11, 20, 24, 31, 33].
Notwithstanding this difficulty, we showed that increasing the stringency of our methodology led to a high concordance with the FREEC-based hits.
Notwithstanding this difficulty in determining the relative abundance of miRNAs, our detection of specific ~21 nt signals for some of the putative new miRNAs demonstrates that they are at least genuine small RNAs and not non-specific degradation products.
Notwithstanding this difficulty validation is of great importance, because an SRR ultimately stands or falls with the correctness of its reason coding – even if it was able to minimize bias when selecting appropriate literature.
Such difficulty notwithstanding, two bond timers did beat the market over the last decade: Paul Merriman Paul Merriman, publisher of FundAdvice.com, and James Schmidt James Schmidt of Timer Digest.
