Sentence examples for this difficulty involves from inspiring English sources

Solving this difficulty involves two winning assets: the definition of modular protocol architecture and the clever use of the object oriented [23, 24] software techniques in order to design a modular software architecture.

Specifically, this difficulty involves two aspects: false-negative sSNVs (true sSNVs not called by the tools) and false-positive sSNVs (spurious sSNVs, either germline SNVs or non-variants).

Part of that difficulty involves confronting space skeptics who wonder whether the mission is worth the cost and risk.

An important disadvantage of this approach is the difficulty involved in selecting a representative sample.

This case demonstrates the difficulty involved in finding the balance between suppressing clinical deterioration due to PML IRIS, which may even lead to death, and halting the progression of PML [ 2].

I can summarize the difficulty involved in this decision in the blank stare I got when I told the bartender at Cervecería Catalana that I didn't eat meat or fish.

However, this approach is limited by the difficulty involved in accessing raw phenotypic data.

This variation on the trumpet was unpopular due to the difficulty involved in playing it.

A leitmotif is the difficulty involved in forming and sustaining human contact.

Current studies are limited by the difficulty involved in collecting fine-scale quantitative environmental data.

Their frustrations begin with the difficulty involved with influencing students' academic decisions.