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The phrase "this difference in" is correct and usable in written English.
You can use it to introduce a comparison between two or more things. For example: "This difference in elevation makes for vastly different vegetation between the two regions."
Exact(60)
This difference in presentation suggests different pathogenic pathways [ 3].
This difference in methodology would have yielded different mortality rates.
This difference in specificity could serve for different staining patterns.
How skewed is this difference in confidence?
Why this difference in birds?
This difference in emphasis may be minor.
Does it change the outcome, this difference in style?
The debates have magnified this difference in preparation and polish.
This difference in preparation persists through elementary and high school.
It grew directly out of this difference in visions".
What causes this difference in wiring?
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com