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Some of the more "classic" effects seem based around this depressant effect.
This depressant is believed to be metabolized by CYP2D6.
This depressant not only must reach the cardiac myocytes but must have a receptor capable of mediating changes in contractility.
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However, this respiratory depressant effect of norbuprenorphine can be antagonized by naloxone (Gal 1989) and also by the substance beta-flunaltrexamine.
This is due to the depressant action on the appetite of the mice and the consequences of disturbed metabolic function and hypoglycemic effect of the parasite [ 22].
This phenomenon was observed within the depressant toxins family from B. occitanus Israelis[ 31].
This phenomenon was observed within the depressant toxins family (Fig. 5), as well as in other families (not shown).
Opioids are known respiratory depressants, and midazolam has been shown to slightly add to this depression in rabbits [ 34].
By contrast, this codon is hardly used in the depressant toxin leader sequence (Fig. 7).
This study was designed to determine whether adenosine A1 and/or A2Areceptor subtypes mediate the depressant effects of hypoxia.
To assess whether this pattern also held true for Boi, the most distinct toxin family, i.e. the depressant toxins, was first examined.
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