Sentence examples for this current topic from inspiring English sources

This Current Topic will review the design and redesign of Zn II -binding sites in de novo-designed proteins and native protein scaffolds toward the preparation of catalytic hydrolytic sites.

Although this Current Topic will focus on the design of zinc metalloproteins, much of the information gleaned from these studies may be applied to the design of proteins coordinating a variety of different metals.

The work described in this section, although focused on structural zinc sites, is important in the context of this Current Topic because it highlights several aspects of metal binding and protein folding that must be considered when designing zinc metalloenzymes.

One example of a de novo protein in which this was done resulted in only one well-folded scaffold that demonstrated a 1 1 binding stoichiometry for Zn II) to the protein (DS119 with βαβ structure, as described earlier in this Current Topic).

The contribution in this Current Topic collection on clocks in algae by Noordally and Millar discusses the gating of cell division by the circadian clock in Chlamydomonas reinhardtii and its initiation coinciding with the beginning of the subjective night (DOI: 10.1021/bi501089x).

As will become apparent throughout the rest of this Current Topic, designed hydrolytic zinc proteins are generally intended to operate by the simple deprotonation mechanism and have not yet encompassed the design of nearby basic residues to assist in deprotonation (a feature of many of zinc hydrolases), nor have they been tested for activation of substrates such as alcohols.

But this year, the current topic is off-limits.

This study addresses the current topic of non-pharmacological conservative treatment of knee OA-related pain.

Keep the current topic of immigration in mind as you consider the future population and government.

Clustering and Mining Software Components for efficient reuse is the current topic of interest among researchers in Software Reuse Engineering and Information Retrieval.

Allow for gross motor activities related to the current topic.