This differential activation could be exemplified by several studies conducted on substances such as BPA, E2, phytoestrogens, diethylstilbestrol [DES] with known differences in affinity for ERα and ERβ, which can induce opposing effects in various cells, tissues, or organs at specific concentration levels [ 6, 18, 27, 43, 60, 61].
In this context, the lack of flexibility in the computing environment could be exemplified through a situation, where the researchers choose 'non-linear-in-parameters' specification.
They could be exemplified as follows: [6.1a] wǒ rènwéi tā zài jiā.
Some defenders of perfect being theology have suggested that it is antithetical to the very idea of perfect being theology that there be perfections that could be exemplified only contingently.
For those who adopt a narrow conception of constraints, x is described with a low degree of specificity (x could be exemplified by the realization of any of a large array of options); for those who adopt a broad conception of constraints, x is described with a high degree of specificity (x can only be exemplified by the realization of a specific option, or of one of a small group of options).
The RPM1-INTERACTING PROTEIN 4 (Ris4) is a well-studied key-player in the former situation [ 5, 6], whereas direct interaction could be exemplified by the R genes and effectors in the rice – Magnaporthe oryzae pathosystem [ 7, 8].
For instance, for the item "getting up after falling" the amputee could be allowed to sit on a mattress on the floor and try to rise up and stand with the help of a chair and "walking while carrying an object" could be exemplified as walking 10 meters while carrying a glass of water.
An alternative reaction involving the generation of an α-CF3 carbanion, from the corresponding bromide 6, allowed the access to the target compound 8, and could also be exemplified in sugar series.
Nevertheless, it is intriguing to speculate that transcriptional reprogramming of aggressive tumour cells may not only cause differential gene expression but also alternative transcript use, which could here be exemplified for a CCNB1 variant.
This could be confirmed by immunohistochemistry as exemplified by the distribution of GFAP which was found only in HSC and cholangiocytes.
