a Control rats: normal neurons are shown condensed, regularly shaped, round nucleous (N) and nucleoulus (NL) in normal cells.
Several critical parameters (drum material, drum speed, condensing cover shape and cooling, brine depth, and weather conditions) were optimized for the new system.
This view is supported both by similar cell characteristics (similar oval shape, condensed nuclei, and proliferation coupled to differentiation) and by similar or shared regulatory molecules, as previously discussed.
Cells that received high dose of radiation showed signs of apoptosis, such as irregular nuclei shape, condensed nuclei, and loss of cellular processes.
In particular, aging is characterized in mice and Drosophila by an increase in the number of muscle nuclei having aberrant shape, condensed chromatin and spatial disorganization (Brandt et al., 2008; Cristea et al., 2010).
Typical necrotic neurons had smaller clumps of irregularly shaped, condensed chromatin with nuclear membrane breakdown.
The cell morphology of untreated cells appeared in elongated shape and treated cells appeared with cellular shrinkage, oval or irregular in shape and condensed cytoplasm.
Signs of immaturity, such as irregular nuclear shape and condensed chromatin deposits on the nuclear membrane, have previously been described in SCARKO-Jsd mice [62].
We observed that EV71 infection induced a typical cytopathic effect of rounded cell shape and condensed nuclei.
The automated image analysis software not only counts the number of nuclei, but also detects aberrations in nuclear shape and condensed chromatin.
In mik1Δ wee1-50 cells at 32 °C, the nucleus condensed to a spherical shape shortly after ceasing movement and entered nuclear division (Fig. 6A), similar to the effect of Cdc25 over-expression (Fig. 5C).
