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Consistent with this conclusion, expression of the dominant mutant transgenes during development tended to decrease the life span of the resultant male and female adults (Supplementary Figure 1A-D, Supplementary Table 1).
Consistent with this conclusion, expression of a functional marker of TEC maturation, major histocompatibility complex (MHC) Class II (HLA-DR/DP/DQ), expression of which is Foxn1-dependent in the early mouse thymic priordium (Nowell et al., 2011), was not detected in human TECs until mid-week 8 (Fig. 3E-F″).
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Consistent with this conclusion, hαSyn expression disturbed the VMAT/CAT-1 GFP expression pattern in L2 organisms before significant DAergic neuron degeneration starts (Figures 4 and 6B), and this disruption persisted in the cat-2 mutant background (Figure S5), wherein DAergic neuron degeneration was preVMAT/CAT-1 GFP
To further verify this conclusion, the expression of Cdk5 was knocked down in control INS-1 cells and in INS-1 cells expressing GFP-β2-syntrophin or the S75D mutant.
Consistent with this conclusion, mRNA expression of Nur77, a key proapoptotic regulator induced during negative selection (Baldwin and Hogquist, 2007), was not elevated in blt/ blt semi-mature SP thymocytes.
In further support of this conclusion, the expression of pro-senescence genes promyelocytic leukemia (PML) and p16 was also increased, while the levels of proliferative marker Ki-67 were decreased in the skin of p53 TSD /− mice (Supplementary Figure S1d).
In conclusion, expression of TACSTD2 was tightly associated with keratinocyte differentiation, and it was expressed in surface epithelium directly facing the external environment.
In conclusion, expression patterns of the two miRNAs in d18-dy were identical to those in wild type (Figure 3A,B).
Conclusion: Expression of SSTR2 and SSTR5 could be important in the growth inhibitory effect of somatostatin in human pancreatic cancer.
In conclusion, expression in P. pastoris improved the yield 20-fold and facilitated the purification of the antibody fragments.
In conclusion expression of genes involved in apoptosis was more pronounced in kidney allografts from deceased donors.
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