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Although it is at present unclear how widespread this phenomenon is, we emphasize that this concern will be alleviated when all polymorphisms can be directly tested (either through complete sequencing or through whole-genome imputation).
This concern will be addressed by means of the short duration of daily restraint and the infants' continued use of both hands outside the treatment time.
However, this concern will be partially mitigated by a similarly lagged response to rainfall in populations of vector species responsible for spreading Plasmodium (Mbogo et al., 2003; Galardo et al., 2009).
We believe this concern will persist for a considerable time because it is related to the culture and the role of healthcare providers as seen by the community of healthcare organizations.
This concern will also be addressed early in the clinical development by testing the safety and immunogenicity of the vaccine in HSV-2 seronegative subjects who are either HSV-1 seropositive or seronegative.
However, as many groups move to whole-exome sequencing or to exon array panels focused on capturing variation in a large number of relevant genes, this concern will become less limiting.
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This same concern will be reflected in the final design of the TKTS booth.
This latter concern will lead on to a consideration of the connection between substance and teleology.
This safety concern will likely limit the scope of investigation for rosiglitazone for AD.
However, this type of concern will be minimal when the sample size is large.
To address this concern, we will be collecting detailed information on concomitant medications and, when necessary, appropriate statistical adjustments will be made.
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