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This comparison is planned for future studies and will be essential to evaluate the potential utility of the approach.
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The control arm will serve as calibration that the populations in the two arms are similar: no statistical comparison is planned between the two arms.
No formal statistical comparison was planned to compare the treatment groups.
As the study's focus was on the safety of NEPA, the APR + PALO group provided context although no formal comparison was planned.
The reasons why four comparisons are planned are to better evaluate the feasibility of this kind of intervention (which could be eventually proposed in the Italian NHS on a routine basis) and to have better insight into its effectiveness, since this may depend on the kind of topics and on the extent of information presented.
No between-group comparisons were planned or performed because of the insufficient sample size and high risk of committing type I and type II errors.
All comparisons were planned and all tests were two tailed.
All comparisons were planned and the tests were two sided.
The Student's t test was used to assess the significance if two comparisons were planned.
All comparisons are planned and all p values will be two sided.
All comparisons were planned, and therefore, no Bonferroni correction was applied.
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