In our model this rate is modulated by the nuclear I κB concentration x11 (indeed, the inhibitor can unbind NF- κB from DNA).
What would you add? Agapi Stassinopoulos: "It takes an inner muscle to please yourself, to ask yourself who is this inner being inside yourself, so you can unbind your human-ness".
We can unbind the queue which is connected to the compromised component and stop receiving messages by the infected client.
In these simulations, ligand-receptor bonds are not stabilized by actin polymerization and can unbind at later times, i.e. remain reversible.
Finally, modified cdr2p in the nodal region, with density ρ nod = N nod / A nod, can unbind and become unmodified cytoplasmic cdr2p at a rate η.
Bound gene-protein complexes that were formed before the current time step can unbind depending on their occupancy status, i.e. with probability k off or k off2, if singly- or doubly-bound, respectively.
Once present on the membrane, with a correspondingly homogeneous density ρ cor = N cor / A cor, cdr2p can unbind back into the cytoplasm at a rate ν, while at the same time becoming modified (e.g., phosphorylated).
Bound gene-protein complexes that were formed before the current time step can unbind depending on their occupancy status, i.e. with probability koff or koff2, if singly- or doubly-bound, respectively.
This saturation is then transferred to the pool of monomers when peptides unbind from the aggregates.
Additionally, most of the Q directly hop over from the Qo to the Qi site and only a few of them unbind from the bc1 back into the bulk.
