In essence, the courts recognize that a statement that is uttered without contemplation or forethought, extemporaneously in the moment, should be considered at trial because people are known to say things impromptu that can implicate them.
If a retired baseball player can implicate the entire sport with steroid charges, if a whistle-blower can rattle the F.B.I., how might just one disaffected ref ravage the N.B.A.'s competitive image?
"They want a veto in sensitive foreign policy issues, including on Israel and Iran — any policy that can implicate the country in a foreign confrontation.
Such tasks are not only sensitive but can also shed light on the specific nature of the dysfunction, and they can implicate dysfunction of specific neural systems, information which can be used to design therapeutic interventions.
This last point is crucial, as point mutations lead to all classes of mutations (e.g., null, hypomorphs, neomorphs, antimorphs, and hypermorphs), which is why forward genetic screens can implicate a gene in a particular process when a targeted deletion may not.
Overall, although more compounds should be tested and analyzed for clear SAR against topoisomerase I and cathepsin B and L, compound 15 showed consistent inhibitory ability on the tested assays, which can implicate the cytotoxic activity of compound 15 on topoisomerase I and cathepsin B and L inhibitory pathways.
Furthermore, proteins that participate in several pathways can implicate multiple biological processes with a single ADR.
Tree edits induced by an SPR operation can implicate lineages that are separated by any number of internal branches.
As can also be seen from the figure, different pathways can implicate multiple metabolites; furthermore, each metabolite can participate in several pathways.
One of the benefits of the integrated genomics approach is that it can implicate biological processes that would not have been detected using differential expression alone.
