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This analysis documented that the CDR2-adjacent epitope (LTFLDD) and the conformational or CDR3 epitope (PPYYL) are responsible for agonist- and antagonist-like activities, respectively.
Interestingly, this analysis documented that the PTPN11 signature displayed highly significant enrichment in targets of tyrosine kinases, particularly SRC family kinases (FYN, LYN, LCK, SRC) and SRC family interacting kinases (CSK, SYK, ZAP70).
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In sharp contrast, however, the analysis documented that the low-oxygen target range 85-899 percentestedted in the experiment had not itself been used clinically when SUPPORT was designed and conducted.
XRD analysis documented that the main minerals of the QS are: quartz, K-feldspar, muscovite, illite, chlorite, as well as minor amounts of pyrite and albite.
Western blot analysis documented that untreated EPCs express very low levels of p16INK4A (Fig. 2A).
The amount of vitellogenin mRNA was quantified semi-quantitatively using actin as an active reference [11].The analysis documented that bees that on average had high numbers of ovarioles and high sucrose responsiveness (HH) also had higher relative levels of vitellogenin mRNA expression than bees with low numbers of ovarioles and low sucrose responsiveness (P = 0.0025; Fig. 2B).
The analysis documented that there was a significant difference in heterogeneity (Wilcoxon signed rank test p = 0.0122), quantified as the sum of Hamming average distances in each region, between the initial (5.546±0.1481 substitutions) and the passaged viral populations (6.464±0.33 substitutions) (Figure 4).
Mass spectrometric analysis documented that the purified CaMKII is unphosphorylated prior to activation (data not shown).
Survival analysis documented that the overexpression of c-Met predicted a worse prognosis (OS: 253 d vs 422 d, P = 0.011).
Overall, the ultrastructural analysis documented that SARS-CoV cultivated in Vero cells behaved like a typical coronavirus, characterized by intracellular budding.
Blot analysis documented that PLC partially counteracted the strong increase of Nox4 protein in the intestinal tissue of the TNBS-treated group (P<0.05).
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