This backstop allows screening for a limited set of toxic end points; early identification of drugs causing the limited set of toxicities is still cost-effective, whereas the subsequent rigorous clinical testing helps protect the public by detecting other types of toxicity.
This network analysis allows screening for possible non tree-like evolutionary events and the influence of phylogenetic noise [ 62].
This allowed screening for differential substitution rates along lineages and for individual genes.
This method allowed screening of embryos with defects prior to the onset of ingestion on embryonic day 5. Morpholino injections that alter the pattern or rate of accumulation of lipid fluorescence, as well as those that produce specific alterations in larval morphology, are recorded.
Hence, the zebrafish Danio rerio is gaining popularity in metabolic research and drug discovery, as this animal model allows screening of small molecules in the context of the whole-organism.
This will allow screening and intervention to occur in smooth succession within schools - an important factor for success and sustainability.
Although this study allowed screening of known genes only, the gene content data still offered new insight on strain relatedness and the distribution and subsequent diversification of mobile elements within the EHEC 2 clonal group.
This also allowed screening for vascular alterations in critically ill patients without the necessity for invasive, time consuming, and, sometimes, risky investigations that are often only performed if focal neurologic signs appear.
We adapted this assay to allow screening of mutant libraries of either l- or d-amino acid specific aminotransferases in a continuous fashion.
Phenotype microarrays could prove useful for this purpose, as they allow screening of a large number of interactions using a simple and time saving approach.
