Sentence examples for this activation persisted from inspiring English sources

We observed that treatment with TRAIL alone and in combination with R-roscovitine was sufficient to activate caspase-8 as early as 8 h after treatment and this activation persisted until 24 h (Fig  5b; top and bottom panel).

This activation persisted after treatment with sumatriptan [4, 33, 34].

Consistent with previous reports (Rostas et al. 1996), tetanus increased significantly the tyrosine phosphorylation of NR2B after 5 min in WT slices (Fig. 5 B ), and this activation persisted until 30 min. However, in hippocampus slices from Irs2−/− mice, tetanus stimulation did not produce tyrosine phosphorylation of NR2B at either of the time points (Fig. 5 B ).

The increased luminescence signal in our transgenic mice unequivocally demonstrated that NF-κB is activated at the initial stage, and this activation persists through the development of DN.

This activation persists for at least 14 days after ICH onset and suggests that the activation of adhesion molecules, especially sICAM-1 and sVCAM-1, plays a patho-physiologic role in the acute phases after spontaneous ICH.

The fact that their activation persisted throughout the entire course of infection (i.e., 12 to 48 hrs) (Figure 3) strongly argues for their important role in regulating epithelial responses to SARS-CoV.

Additionally, the increased p38MAPK/MAPKAPK-2 activation persisted in H2O2-treated cells.

Smad activation persisted in the muscle reinnervation phase out of proportion to total Smad expression.

Importantly, JNK activation persisted and increased in time during synaptopathy progression in TgCRND8 mice.

In addition, heat-induced transcriptional activation persisted when hrde- 1 mutant was shifted back to 15 °C.

Moreover, microglial activation persisted regardless of the presence or absence of Lewy bodies and was frequently associated with damaged neurons and neuritis [ 13].