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The need to have a reliable and inexpensive predictor of response in a third world scenario can not be over emphasized since majority of patients present relatively late and the resources are limited and scarce [ 2, 3].
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However, in health care settings where approval of expensive drugs along the lines of first-world scenarios is not affordable, knowledge about the high risk of recurrence in HER2+ HR- patients might help to devise subgroup-specific surveillance or anti-HER2 treatment strategies in this circumstance.
Following the Second World War, scenario planning has been widely used for businesses in response to the failure of quantitative models (Table 1).
Before each hit and run mission (all based on genuine second world war scenarios), you must select three differently skilled soldiers.
IT SOUNDS like the opening lines of a military planner's scenario for the third world war.
The evolution of functions that are associated with corresponding FFs along the timeline reveals that primordial metabolic domains evolved earlier than informational domains involved in translation and transcription, supporting the metabolism-first hypothesis rather than the RNA world scenario.
The Zn world scenario shows how the "metabolism first" and "replication first" concepts can be reconciled and combined.
Such a scenario could force the Third World countries into yet another dilemma similar to what the community of states faced in the 1950s and 60s.
The Zn world scenario implies that the first RNA-like oligomers emerged within the illuminated ZnS compartments.
This is all the more surprising because "the end of the world" is an archetypal theme with a sonorous label – eschatology – that morphs in popular culture into many doomsday scenarios, from global warming to the third world war.
The idea of porous natural settings as incubators for the first RNA-like life forms is used in the Zn world scenario.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com