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The phrase "think upstream" is correct and usable in written English.
It can be used in contexts where one is encouraged to consider the broader implications or root causes of a situation rather than just the immediate effects. Example: "In order to solve the ongoing issues in our supply chain, we need to think upstream and address the problems at their source."
Exact(1)
There are three key areas to concentrate on to become a successful sales manager: You need to teach your team to think "upstream".
Similar(59)
"I think we were swimming upstream against a lot of anger and fear generated by the Trump campaign, and it trickled into our area," Farrell said.
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In Arabidopsis, it has been reported that AtPHT1 4 was induced by sucrose and is thought to be upstream of the hexokinase sugar-sensing pathways (Lejay et al. 2008).
Since beta-amyloid accumulation and impairment of ERAD and UPR functions are thought to be upstream events in sIBM development [16], our data points to RNF5 deregulation as an early event in the onset of the disease.
Similarly, ARF4 and the related ETT/ARF3 gene are thought to function upstream of the YABs [ 44].
Significantly, two of these target genes, KAN1 and ARF4 are thought to lie upstream of the YABs.
A two-component histidine kinase 1 (ATHK1) is reported to function as an osmosensor, and phospholipase C PLCC) is thought to function upstream of the drought-responsive DREB2 system [ 76].
Xdsh is thought to act upstream of β-catenin (Clevers 2006) and in order to promote dorsalization, Xdsh should reside in the nucleus (Itoh et al. 2005).
These processes are thought to be upstream signals leading to the activation of critical Hsfs, which are most likely the direct inducers of Hsp20 expression under stress.
To investigate further the pathway of SAPK activation during ischaemia, we assayed the kinases thought to lie upstream of p38 and JNK.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com