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THIN data collection was approved by the NHS South East Multi-centre Research Ethics Committee (MREC) in 2003.
Data are coded using drug codes which correspond to British National Formulary (BNF) chapters 24 and Read codes (V.2). 25 THIN data collection was approved by the NHS South East Multi-centre Research Ethics Committee (MREC) in 2003.
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Our goals include building a thin layer of data collection infrastructure on top of the existing data collection systems of health care and other industries".
Additional analyses that the authors might wish to carry out (but not required for review) include use of several smaller and thinner crystals for data collection and a quantitative effort to get a lower R-factor by an explicit attempt to model the dynamical scattering quantitatively.
Recently, a per-particle CTF correction method in 3D for cryoSPT was proposed (Galaz-Montoya et al. 2015) and demonstrated in vitro at near subnanometer resolution, without making any of the aforementioned assumptions (accurate defocusing during data collection, thin ice, unbent specimen, etc)., using only a few hundred icosahedrally symmetric virus particles (Galaz-Montoya et al. 2016a).
Accessible publications that describe verbal autopsies are thin on detail about data collection.
Because of further advances in sample preparation (receptors locked in a single state), data collection (thinner sample, direct detector), and processing (contrast transfer function correction), we are now often able to visualize CheA dimers individually in tomograms within intact arrays.
Recorded information on cancer has been validated in a related database (General Practice Research Database), which shares some practices with THIN and uses the same electronic software for data collection (37).
The authors show themselves with their simulations that the data collection strategy they use generates severe artifacts to thin structures that are perpendicular to the beam.
For plastic sections, the initial exposure to the beam causes thinning of the sections, but subsequently the sample changes little during data collection.
Another advantage of the use of thin films of extracellular matrix proteins is that they facilitate unbiased automated fluorescence microscopy data collection and analysis.
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