The sensitivity and specificity for thickness values outside normal limits were: m-RNFL (p<5%): 0.74 and 0.93; m-RNFL (p<1%): 0.61 and 0.96; GCL+IPL (p<5%): 0.48 and 0.88; GCL+IPL (p<1%): 0.42 and 0.90 (sensitivity and specificity, respectively).
However, for maintaining high degree of specificity and sensitivity, thickness and coverage of Au immobilization layer can be carefully optimized to minimize TCE-induced deflection.
Recently, a multivariate classification study of cortical thickness demonstrated 82% sensitivity and 85% specificity for differentiating AD from DLB [ 43].
Table 3 shows the estimated sensitivity and specificity to detect retinal thickness changes by OCT with the two LCA models.
Examination of the rotator cuff using MRI is highly correlated to surgical findings for full thickness tears, having a sensitivity and specificity of 85% and 83% for first-time shoulder surgery, and 84% and 91% for failed repairs [ 45].
Far less common, acromioclavicular and intramuscular cysts are mainly but not necessarily associated with full- or partial-thickness rotator cuff tears, their presence improving the sensitivity and specificity of MRI detection of partial-thickness tears [14].
Surface-based morphometric analyses should complement volumetric findings, providing more specificity in the metric affected (thickness vs. gyrification).
Best performance trade-offs for sensitivity and specificity were found for cortical thickness and grey-white contrast (Figure 5), followed by, in descending order, LGI, sulcal depth and jacobian.
A recent systematic review shows that MSU has a sensitivity of 95% and a specificity of 96% for full thickness rotator cuff tears, and a sensitivity of 72% and specificity of 93% for partial thickness tears when performed by an experienced radiologist [ 17].
Several authors have reported excellent MRI detection of full-thickness rotator cuff tears, with sensitivity and specificity both above 90% (Iannotti et al. 1991, Wang et al. 1994, Balich et al. 1997, Waldt et al. 2007, De Jesus et al. 2009).
