While we expected that brightening would desensitize the photoreceptor output (black) and dimming would sensitize it (Figs. 5C D), the general sensitization of the corresponding LMC output (Figs. 5C, E, gray) has not been reported before.
"I felt that the men here are taking steps to make changes in their lives and that this would sensitize them, both in coming to terms with what they've done and the victimization of what's been done to them," Ms. Merritt said.
It was expected that ABT-737 would sensitize the etoposide-resistant cells for cell death induction, in case they overexpressed Bcl-2 or other ABT-737 target proteins.
Since MCF-7 5C MCF-7 5C4 breand cancer cells are resistant to tamoxifen and they express low levels of PEDF, we next examined whether staBT474xpression of PEDF in these cells would sensitize them to the inhibreast effecancer tamoxifen.
We hypothesized that the RNA interference (RNAi) induced by retrovirally delivered small interfering RNA (siRNA) would sensitize pancreatic adenocarcinoma cells to gemcitabine and attenuate their invasive potential.
The hypothesis was formed that pre-exposure to the compound would sensitize breast adenocarcinoma (MDA-MB-231) cells to gamma radiation, in pathways dependent on reactive oxygen species (ROS) generation.
This study was designed to evaluate whether gossypol, a phytochemical compound with BH3-mimetic property that functions as an inhibitor of Bcl2/BclXL, would sensitize cultured thoracic cancer cells to this death-inducing ligand.
Because the UPR is an important cytoprotective mechanism, we hypothesized that bortezomib would sensitize pancreatic cancer cells to ER stress-mediated apoptosis.
We also determined whether prenatal nicotine exposure would sensitize the brain to a subsequent postnatal episode of hypoxia comparable to that experienced during parturition.
Because these results demonstrate that mitochondria are an important in vivo target of arsenite toxicity, we hypothesized that deficiencies in mitochondrial electron transport chain genes, which cause mitochondrial disease in humans, would sensitize nematodes to arsenite.
