Sentence examples for they deletions from inspiring English sources

Chromosomal abnormalities, that is to say large scale alterations to the DNA, be they deletions, duplications or translocations, can have more severe effects.

Cancer cells can become resistant to a PARP1 inhibitor if they undergo deletions of mutations in BRCA2, undermining the drug's synthetic lethality by restoring cancer cells' ability to repair DNA by HR.

They observed deletions and inversions at all sites, and duplications in Pitx1 and Laf4 with 0.7 % and 28.1 % frequency, respectively.

Usually they order deletion or site closures, rather than issuing directives in advance.

Depending on the TCR β chain, they observed deletion of CD4+ T cells of 36 up to 42% [18].

CNVs are different genetic variations from SNPs, in that they are deletion or amplification of DNA fragments but not single-nucleotide polymorphisms.

Thus, in spite of the thymic cortex being largely devoid of DP thymocytes in male mice, some cells develop normally if they escape deletion by the early expression of endogenous TCRα chains.

They found deletion mutant of BRAT1 in patient, however it remains to be clear how this mutation affect disease development.

Cases were assigned to the Del+ group if they had deletion of both 1p and 19q, or 1p alone.

They suggested deletion of end of life care and medication safety because these were not as immediately relevant to HCAs' core scope of practice.

CNVs might change the transcription rate of a gene product by increased or decreased transcription, in case of deletions, they may unmask recessive mutations, or they might change the coding sequence of a gene.