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This suggests that, while both pharmacophores are competitive inhibitors of NADH-binding, they bind to the pocket in different ways.
PDCD4 also binds eIF4G-MIG without affecting eIF4A binding as they bind to diametrically opposite sides of eIF4A [ 28].
They bind to the proteins in our saliva, inhibiting its ability to lubricate the mouth, causing a puckering, astringent feeling.
They bind to the chemicals in order to move them across the cell membrane.
They bind to the receptors protruding from the tumor cell surface, preventing the intended growth factor from binding.
They bind to double-stranded telomeric DNA as homodimers.
Therefore, at low concentrations, they bind to the activated receptors only.
They bind to target molecules by folding into 3D structures that can discriminate different chiral compounds.
The smallest barrels form inverse micelles and work as enzymes or they bind to other macromolecules.
Mimicking natural estrogens, they bind to estrogen receptor and modulate its activity.
Stoddard's laboratory examined how proteins behave, how they move, what they bind to and how.
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