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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
they are indispensible
Grammar usage guide and real-world examplesUSAGE SUMMARY
✓ Grammatically correct
Science
News & Media
Encyclopedias
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
5 human-written examples
Restriction enzymes can be isolated from bacterial cells and used in the laboratory to manipulate fragments of DNA, such as those that contain genes; for this reason they are indispensible tools of recombinant DNA technology, or genetic engineering.
Encyclopedias
Now they are indispensible for the campaigns to reach out to their public, young and not-so-young alike.
News & Media
They are indispensible components of global climate action.
News & Media
They are indispensible for the basic catalytic function of the enzyme complex and comprise all mtDNA encoded subunits and seven nuclear encoded subunits, which contain the redox groups and most components of the proton translocation machinery [19], [20].
Science
It has been suggested that duplicated genes are mainly saved from removal through functional diversification, because of positive gene dosage effects, or because they are indispensible parts of a protein network, e.g. as subunits in an enzyme or signalling complex [ 102, 106- 110].
Science
Human-verified similar examples from authoritative sources
Similar Expressions
55 human-written examples
They provided man with transport (in both love and war) and they were indispensible partners down on the farm, when agriculture accounted for the vast majority of economic output.
News & Media
We found that angptls1 and 2 are indispensible for zebrafish definitive hematopoiesis and that they genetically interacted with notch signaling.
Science
But both men say their experiences with a range of drugs are indispensible in helping their members.
News & Media
External power supplies with variant voltage output are indispensible for powering devices without integrated internal batteries.
Science
We propose that interfacial parameters are indispensible tools for the design of electrospinning experiments.
Science
High-reactivity electrode materials are indispensible for developing high-performance electrochemical energy storage devices.
Science
Expert writing Tips
Best practice
When using "they are indispensible", ensure the context clearly establishes what "they" refers to. This maintains clarity and avoids ambiguity.
Common error
Avoid overusing "they are indispensible" in contexts where "they are important" would suffice. "Indispensible" suggests something is absolutely necessary, not just helpful or significant.
Source & Trust
87%
Authority and reliability
4.4/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "they are indispensible" typically functions as a predicate adjective, describing the essential quality of the subject (they). Ludwig shows its use in expressing necessity across varied contexts.
Frequent in
Science
60%
News & Media
20%
Encyclopedias
20%
Less common in
Formal & Business
0%
Wiki
0%
Reference
0%
Ludwig's WRAP-UP
In summary, the phrase "they are indispensible" is used to emphasize the critical necessity of something. While grammatically correct, as confirmed by Ludwig, it's less common than its synonym "indispensable." Its usage is primarily found in formal and scientific writing, making it suitable for contexts where precision and clarity are paramount. When using this phrase, ensure the referent of "they" is clear to maintain coherence. Alternative phrases like "they are essential", "they are crucial", or "they are vital" can offer broader accessibility without sacrificing the intended meaning.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
they are essential
Replaces "indispensible" with a more common synonym while retaining the original meaning of being absolutely necessary.
they are vital
Substitutes "indispensible" with "vital", emphasizing the critical importance of the subject.
they are crucial
Uses "crucial" instead of "indispensible" to highlight the decisive role of the subject.
they are critical
Replaces "indispensible" with "critical", stressing the importance of the subject to avoid failure.
they are paramount
Emphasizes the supreme importance of the subject, making it top priority.
they are requisite
Replaces "indispensible" with "requisite", indicating that the subject is required or necessary.
they are mandatory
Uses "mandatory" instead of "indispensible" to denote that the subject is compulsory.
they are non-negotiable
Replaces "indispensible" with "non-negotiable", highlighting that the subject cannot be compromised.
they are irreplaceable
Substitutes "indispensible" with "irreplaceable", indicating that the subject cannot be substituted with something else.
they cannot do without
Expresses the indispensability by explaining that it is impossible to do without the subject.
FAQs
What does "they are indispensible" mean?
The phrase "they are indispensible" means that something is absolutely necessary or essential. Without it, something would be incomplete or impossible.
What's a more common synonym for "they are indispensible"?
A more common synonym for "they are indispensible" is "they are essential". Other options include "they are crucial" or "they are vital".
How can I use "they are indispensible" in a sentence?
You can use "they are indispensible" in a sentence like, "In recombinant DNA technology, restriction enzymes are indispensible tools."
Is "indispensable" or "indispensible" the correct spelling?
"Indispensable" is the standard and more widely accepted spelling. "Indispensible" is less common but recognized. Always check your audience and publication guidelines.
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Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
87%
Authority and reliability
4.4/5
Expert rating
Real-world application tested