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These residues were individually substituted with alanine.
These residues are ~15 Å apart so these residues should have reduced disulfide formation.
These residues have no use in the industry and cannot be recycled".
The Prif experts concluded: "We do not expect these residues to have an effect on health".
In the tainted bottles of Coke, these residues were present at levels of between five and seventeen parts per billion.
These residues lie deep in the pocket on the TAS2R16 homology model (Fig. 8).
These residues are located at TM2 and lining pocket 1 (Fig. 5b).
These residues are over 40 Å away and should form disulfides poorly.
Hence, while important, these residues are not absolutely essential to MCR-1 function.
These residues are all displayed at the same side of the molecule.
Note that Pmp23 possesses all these residues (E61, D68, E74, N119).
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