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Prior to asymmetric division, these fate determinants are differentially enriched at either of the apical or basal pole, in which the mitotic spindle apparatus and centrosomes are unequally aligned.
These fate decisions are dependent not just on the soluble chemical cues that are encountered or enforced in vivo and in vitro, but also on physical cues from the cellular microenvironment.
We examined levels of caveolin-1 in satellite cells after 72 hrs of culture, when these fate choices are being made, and found that caveolin-1 immunostaining was stronger in the cells not containing myogenin, and so not yet udergoing myogenic differentiation (Figure 5).
On the other hand, the transcriptional networks controlling these fate decisions are still largely unknown.
These fate restricted cells then populate lateral regions of the regenerative blastema, specialized mesenchymal tissue formed upon amputation.
These fate processes depend on both the characteristics of the particle and the characteristics of the environmental system (Boxall et al. 2007).
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As they seem to be heading in separate directions, these fate-driven films can be seen as a kind of trilogy.
No love potions are required for these fates to be fulfilled.
These fates are a shocking reminder of a global problem caused by global warming.
In rich countries, governments can spend tax revenues to ensure these fates are avoidable.
These Fates-in-training, especially the slit-eyed Ms. Barden, give "Tamara Drewe" a spark of real mischief.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com