What these examples emphasize is that first, despite the pervasive nature of histone PTMs, specific cancer phenotypes arise from alterations in the chromatin PTM landscape and, second, there may potentially be many other histone modifications of equal or greater importance in cancer biology.
Several examples emphasize that it is important to evaluate a newly installed system objectively and correct the problems encountered.
Thus, this example emphasizes that anxiety must be considered as a comorbid condition in the treatment of asthma.
For ET/PT, the change in Q that induces ETa includes the Q displacement required for PT1, but the PT takes place only after ET. This example emphasizes that, in general, the theoretical modeling of PCET reactions requires two different nuclear reaction coordinates for ET and PT, as described by Borgis and Hynes or by Hammes-Schiffer and co-workers (see Figure 25b).
We highlight these examples to emphasize that "successful pioneers" must arise from a subset of the individuals that leave the historic range.
Galileo's marvelous Letter to the Grand Duchess Christina, for example, emphasizes that Scripture responds to a completely different kind of question from those of science.
Corner, for example, emphasizes that his master plan for Fresh Kills is a "strategy, not a design in any rigid sense," and his "Lifescape" title recognizes the role that natural processes will play over this 30-year metamorphosis.
This episode helps bring closure to this section of the book with yet another example emphasizing that sketching is a language that supports a particular form of dialogue a dialogue that can help everybody bring the ideas one step closer to fruition.
CaliBurger, for example, emphasizes that the software it uses will not store the facial images.
