Sentence examples for these differentiation from inspiring English sources
Although these differentiation models do not lead to terminally differentiated erythrocytes analyzed in our study, we note a high degree of similarity in the microRNAs seen during the earlier stages of erythroid differentiation investigated in these studies and the microRNAs reported here in mature erythrocytes.
The establishment of neurectoderm or mesoderm to the exclusion of the alternate outcome suggests that the manipulations used in these differentiation methodologies act to alter lineage choice from differentiating EPL cells.
These differentiation protocols allow access to cell populations, including transient developmental progenitors and terminally differentiated cells that would otherwise be unattainable from human tissue.
Both of these differentiation antigens are expressed on >90% of melanomas [46].
Therefore, we decided to test this hypothesis by focusing on defined stages of these differentiation programs.
It cannot be excluded that HP1γ contributes to the repression of these differentiation genes.
These differentiation states can be further subdivided into stable and transitory subtypes, which altogether are assembled into a dynamic "ecosystem".
With these maps of the differentiated state in place, a central task is now to unravel the chromatin dynamics that enables these differentiation transitions.
The original definition of these differentiation stages is derived from the measurement of CCR7 and CD45RO [33]; however, others have used CD27 and CD45RO to assign these stages [32], [35].
We only detected procyclin in PCFs and PAD1 was exclusively detected in stumpy cells, suggesting that knockout of RabX1 or RabX2 did not lead to expression of either of these differentiation markers (Figure 10B).
Collectively, these data revealed an intriguing picture of a general upregulation of diverse mesenchymal differentiation markers in p53 KO MEFs, which suggest an inhibitory role for p53 in these differentiation pathways.
