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These data pose the intriguing question of whether BMLs encode key clues to the aetiology of OA.
Moreover, these data pose a fundamental question in the rat MCLT + MMT model of knee OA: Will therapeutics that prevent or reverse cartilage degeneration following a simulated meniscus injury have efficacy in treating OA-related symptoms and disability?
Although it is possible that different injuries result in similar disease sequelae in the rat, these data pose a fundamental question for preclinical OA models: Will therapeutics that prevent or reverse cartilage degeneration following a simulated joint injury have efficacy in treating OA-related symptoms and disability?
Considering the hyperthermia induced G2/M cell cycle defects observed in the breast cancer cells but not the mammary epithelial cells, these data pose the question as to whether hyperthermia may function in a synergistic manner when combined with drugs that specifically target mitosis such as taxols and vinca alkaloid derivatives.
- These data pose the question as to whether the equilibration of albumin through the stack within 1-2 min can be best explained by a model based on simple diffusion of albumin between the cisternae through tubules without biasing forces, or by a model based on vesicular transport.
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The ordinal nature of these data poses a practical problem, and so does the existence of two scales per variable.
However, the generation of these data poses an extreme computational burden that is impractical for large populations.
These characteristics of the data pose the following challenges for existing methods.
These additional characteristics in the data pose additional challenges to a fixed-feature representation driving selectivity and behavior for the images and producing the correlation between neural and behavioral response seen in Fig. 3A.
Limitations of the data pose some challenges for interpretation of results.
Nevertheless, the data pose some limitations.
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