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These data identifying some of the molecular events and biochemical pathways associated with plaque vulnerability may help in the development of new strategies to prevent plaque rupture.
Short-term apoptotic cytotoxicity, as well as a long-term clonogenic cytotoxicity response, emerges from these data, identifying clusterin as a death-inducing gene (Leskov et al, 2003).
Univariate analysis (Cox model) further confirmed these data, identifying ER-β+ as a significant predictor of better DFS in the 210 node-negative patients in the HT group (hazard ratio [HR] 3.033, confidence interval [CI] 1.077 to 8.539, P = 0.036) but not in the 240 patients in the CHT group (HR 1.265, CI 0.586 to 2.729, P = 0.55).
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These data identify a previously unrecognized mechanism of the anti-tumor effects of arsenic trioxide.
These data identify a transcriptional circuit critical for B cell lineage commitment.
These data identify molecular features for patient stratification and uncover a potential targeted treatment approach for MYC-driven SCLC.
Collectively, these data identify subnuclear localization as an important regulatory mechanism for telomere length homeostasis in human cells.
These data identify TRβ in the VMH as a major physiological regulator of food intake and energy homeostasis.
These data identify a proinflammatory phenotype within the prefrontal cortex of mice fed a western diet, and indicate that chemokine induction can be blocked by voluntary exercise.
These data identify multiple noncanonical endpoints that are pivotal for rational design of hedgehog modulators and provide a new therapeutic avenue for obesity and diabetes.
In summary, these data identified SIRPα signaling in non-hematopoietic cells to play an important role in regulating the numbers and positioning MZB cell in the spleen.
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CEO of Professional Science Editing for Scientists @ prosciediting.com