Sentence examples for therefore upregulated from inspiring English sources

PGF-1 is therefore upregulated in the retina of GK diabetic rats, increasing at the early stages of diabetes and remaining elevated thereafter.

Therefore, upregulated genes may be more involved in the process of tumor formation compared to downregulated genes and 2(c)).

Therefore, upregulated PTEN expression induced by HDAC inhibition would enhance the cytotoxic effect of PARP inhibitors in PARP inhibitor-resistant breast cancer cells.

Therefore, upregulated FGFR1 expression may compensate for the reduced expression of VEGFa/b observed in network 2. Work from our group and others have previously implicated abnormal FGFR1 expression in prostate carcinogenesis (Devilard et al, 2006; Acevedo et al, 2007; Sahadevan et al, 2007).

Therefore, upregulated NF- κB activity has been reported in different tumor types including laryngeal and pancreatic cancers [ 34– 34].

Taken together, the concept that ANXA1 is "oncogene" and therefore upregulated in GC requires a new looks on the basis of our data.

Therefore, upregulating HIF might be a superior strategy to promote the angiogenic process.

In SAD patients, however, this particular connection exhibits positive, excitatory effective connectivity, and, therefore, upregulates amygdalar activation.

Whilst agents that inhibit DNA methylation are therefore being actively investigated as potential therapeutic agents in prostate cancer, one issue that also needs to be considered is their potential to hypomethylate and therefore upregulate genes involved in metastasis.

MetE is thus essential for methionine synthesis in a methionine-dropout medium, and is therefore greatly upregulated under these conditions34.

Moreover, FLIP is the product of an NFκB target gene (CFLAR) and therefore is upregulated following TNFR1 ligation.