Exact(2)
Therefore, this conformation of the farnesyl chain is consistent with TEAS preorganizing FPP (or more likely the resultant acyclic farnesyl cation) for cyclization to 5-epi-aristolochene (1), in contrast to the original TEAS·FHP complex 5).
When in phage, the sequence could to assume a favorable position to act as binder of antibodies [ 29] and therefore this conformation could disappear when used as synthetic peptides.
Similar(58)
Finally, the left-handed helical filaments were crystallized at a lower pH solution [22], and it was suggested, therefore, that this conformation might be an artifact of this particular crystallization condition.
Superimposition of the PKA ATP peptide complex (PDB code 1ATP) revealed that a docking groove created within the active site of GAK would be suitable to accommodate a peptide substrate, which therefore suggests that this conformation of the activation segment may serve as an active conformation of the enzyme to enable peptide binding.
Therefore, this down-cis conformation of NikR corresponds to a specific binding conformation that can recognize and bind the nik operon with the measured "high affinity" or nanomolar dissociation constant (2, 4).
Therefore, the conformation of PVP makes the fine and close adsorption on the (100) facets of silver nanocrystals.
Therefore, the conformation of polyA's in the aging step was first examined.
Therefore, the conformation transition of the hexyl tail is critical and required for hydrolysis of covalent-orlistat.
Therefore, the conformation of the receptor and the presence of two distinct binding sites allow the receptor to specifically select HpHb over its two constitutive components.
Here we show that the gp120 Phe 43 cavity modulates the propensity of Env to sample this conformation and therefore affects the susceptibility of infected cells to ADCC.
Therefore these conformations would appear to be compatible with receptor binding, but only the Z isomer has an energetically allowed extended conformation that accounts for its observed biological activity relative to DES.
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