The question of whether opsin is a reliable template for modelling activated and basally active GPCRs is therefore open to discussion and is likely to remain so until additional crystal structures of active GPCRs emerge.
Tillberg argued: "The usefulness of reposition and nailing of femoral-neck fractures in elderly patients is therefore open to question, and primary arthroplasty is recommended instead".
Another limitation was that our study was not blinded and was therefore open to problems of observer bias.
He also argued that many aspects of the bill, including specifically the language around encryption, is too vague — and is therefore open "to interpretation".
Our data on medication use and health care utilisation are based on self-reports and therefore open to recall bias, although there is no reason to suspect systematic bias.
Trump voters, we are informed, are the victims of economic competition from abroad, and are therefore open to his populist pandering about immigration and trade.
And these works are less divisive than religious texts because their insights are not contingent on the acceptance of a particular mythology, are based on reason, not revelation, and are therefore open to discussion and more responsive to the continually changing conditions we find ourselves in.
Duyệt wanted to further give tax concessions to newly arrived Chinese immigrants that were deemed to be impoverished to encourage immigration and speed up development of the region, something that the emperor was sceptical of, on the reasoning that it was difficult to genuinely determine who was in need and that the concession system was therefore open to rorting.
Unlike Mr. McCain and Mrs. Clinton, Mr. Obama is relatively new to national politics and is therefore open to bringing new people — and new money — into the tent.
This evidence is therefore open to the interpretation that, in those with small coronary arteries, higher activity levels are associated with greater risk of infarction.
