Sentence examples for therefore necessitating from inspiring English sources

However, this is not feasible for most cases, therefore necessitating the utilisation of an instrumental function π(x t ) (as in [32]), with the p(x t |x t−1) function.

Initial in vivo stability as well as ex vivo biodistribution studies demonstrated excellent in vivo stability of the tracer and uptake in NSCLC xenografted mice, although no large differences with regard to uptake between wild-type (WT) and the exon 19 deleted mutant of EGFR were observed in ex vivo biodistribution studies, therefore necessitating further PET studies described in this work [21].

In one patient, left ventricular ejection fraction dropped below 50% without symptoms, therefore necessitating a discontinuation of therapy.

Second, adult patients may have required more complex overall care, therefore necessitating the additional knowledge and skills of a dentist.

In recent years, the increase in human populations resulted into negative effects on water quality, therefore, necessitating the formulation of a good management strategy of water resources in this area (Hosseini et al. 2009).

This could be explained by a steeper closure angle of the ON-X (40°) when compared to the other valves (not more than 25°), therefore necessitating a larger leaflet volume.

To this end, it was necessary to realistically model the various attributes of nonlinear response of both the structural element (RC column) and the soil foundation interface, therefore necessitating the use of the following: (1) A new scale model reinforced concrete 38 capable of replicating stiffness, strength, failure mode, and post-failure response of the bridge pier.

While the answer is not clear, the combined implication of the data is that B lymphocytes do play a role in human carcinoma development, therefore necessitating a mechanistic evaluation of their role and specificity to determine whether they represent tractable targets for anticancer therapy.