Therefore, inhibiting the EGFR can downregulate the expression of these targets, facilitating their inhibition by target-specific agents.
Therefore, inhibiting Axl function may represent a potential target for future antiviral therapies.
PrCa often remains indolent, but if the disease progresses into advanced stages, no cure is currently available.51 A therapeutic option is therefore inhibiting invasion when instigated.
We envision that KH176m might in fact alter the transmission of such signal when interacting with the peroxiredoxins and therefore inhibiting the cell death signalling triggered by the BSO treatment.
Ta was found to exhibit a beneficial effect by promoting the formation of NaTaO3 and TaS2, and therefore inhibiting the formation of liquid phases Na2MoO4 and Ni-sulphides.
Therefore, inhibiting both HGF/c-Met and VEGF/VEGFR signaling may provide a novel and effective therapeutic approach for treating patients with abroad spectrum of tumors.
PARP-1 could repair the DNA damages induced by Topo inhibitors, therefore inhibiting Topo and PARP-1 simultaneously might be able to overcome resistance and improve outcomes.
Therefore, inhibiting the UPP may be an effective approach to treat MM (Landis-Piwowar, 2012).
Therefore inhibiting a single target of such a network might not lead to the desired therapeutic effect.
The Hippo pathway consists of a kinase cascade, and therefore, inhibiting upstream kinases represents an ideal approach to activate YAP/TAZ.
Therefore, inhibiting the function of one protein might be insufficient to restore pRB levels and function.
