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One patient was found to carry a de novo 9bp deletion in TSC2, which was out of frame, therefore deleting four amino acids and inserting an arginine in a highly conserved domain of the protein.
Therefore, deleting a single Cx gene is unlikely to totally eliminate intercellular ionic coupling since the remaining Cx gene is still able to function and form homomeric GJs.
Therefore, deleting the rpoN gene would result in deficiencies in ammonia assimilation and thus, cell death.
Therefore, deleting BLIMP1 would block the differentiation of B cells into plasma cells.
Therefore, deleting the entire new13 ORF removed sequences encoding the C-terminus of Dsc4 and vice versa.
Therefore, deleting either ASIC2 or ASIC3 will disturb the assembling of heteromeric ASIC2/3 channel, which might play a role in autonomic regulation [ 38].
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Moreover this term equals the revenue derived from the tickets that appears in the transport system cost, therefore both terms appear in the cost function with opposite signs, and therefore delete each other.
We therefore deleted these genes either alone or in combination and crude cell free extracts prepared thereof were used in an in vitro assay to measure the strains ability to break down acetyl-phosphate over time (Fig. 4).
If for some reason the server is no longer able to establish a connection or send a message to a client, the client is considered unreachable and is therefore deleted from this table to prevent further wasting of resources.
We therefore deleted each of these factors singly or in combination and analysed S-phase progression by FACS analysis.
We therefore deleted RPD3 in strains carrying different combinations of histone lysine (K) to arginine (R) substitutions and determined which mutations would revert the more rapid S-phase.
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