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Since annexin V binds to PS with high affinity, therefore, binding of PS to a fluorescent-tagged annexin V can be used for detecting apoptosis at its earlier stages with a fluorescent-detecting system, such as flow cytometer or fluorescent microscopy.
Therefore binding measures are unavoidable.
Therefore binding site comparison methods may have an important role in identifying the polypharmacological activity of molecules.
However, the use of the DNA duplex stability data is limited because little verified information about TF binding specificities can be found from the literature and, therefore, binding specificities need to be learned from the data as well which currently requires that a set of verified binding sites is known.
Since the Declaration has been signed and ratified by the United States it is therefore binding on state governments through the Supremacy Clause of the Constitution (Article VI, clause 2).
Therefore, binding to H3K27me3 is essential for LHP1 protein function.
Similar(18)
Therefore, binding-site residues and residues exposed in the protein surface should behave similarly with respect to flexibility.
Therefore, calcium binding and GTP binding inversely regulate the conformational state of TG2, as well as the transamidation activity.
Therefore, this binding site was discarded, and we focused on the binding site CAV for the subsequent steps.
We therefore performed binding assays at 37°C to verify the stability of the binding of the aptamer to its target.
It seems therefore that binding to δ' confers a specific conformation on γ, priming for binding to δ.
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